"Talc acts as both a glidant and lubricant during tableting, and as a polishing agent for tablet coatings. Talcs are chemically inert, oleophilic and hydrophobic, and have relatively high oil absorptions. Being the softest mineral, by definition as 1 on Moh’s scale of hardness, talcs have very low abrasion, protecting expensive tablet dies and other machine parts." (Specialty Minerals).
Este es el espectro NIR del talco. Se trata de un espectro muy interesante por la banda aislada que presenta a 1392 nm aproximadamente. Esta banda es ampliamente utilizada en muchos estudios de diagnósticos de un equipo NIR como son la repetibilidad y la resolución.
Podemos realizar el análisis de la muestra en un número determinado de ocasiones, anotando el valor de absorción del equipo en cana uno de ellas y posteriormente realizar la desviación estándar, para calcular la precisión.
La intensidad de esta banda aumentará o disminuirá también según sea la resolución de los equipos. No obstante tenemos que tener en cuenta que la repetibilidad también será mejor o peor en función de la resolución y por tanto de la intensidad de la banda.
Por tanto aquí se presenta un dilema: ¿Queremos una mayor intensidad de la banda? o ¿Queremos una mayor repetibilidad?.
Esta claro que las dos opciones tienen sus ventajas, pero debemos de tener en cuenta que la precisión es de gran importancia a la hora de cualificar o cuantificar la repetibilidad es muy importante. No obstante a la hora de detectar trazas de esta banda (de la presencia de talco) el aumento de la resolución nos ayudará.
Esta banda nos permite hacer el cálculo de la relación señal ruido de los equipos.
This is the NIR spectrum of talc. This is a very interesting spectrum for the isolated band presented at 1392 nm. This band is widely used in many studies of NIR instrumentation such as repeatability and resolution.
We perform the analysis of the sample in a certain number of occasions, and then we make the standard deviation of the absorbance values obtained to calculate the precission.
The intensity of this band also increase or decrease according to the resolution of the equipment. But we must know that the repeatability will also be better or worse depending on the resolution and therefore the intensity of the band.
So here is a dilemma: Do we want a greater intensity of the band? or Do we want a better repeatability?.
It is clear that both options have their advantages, but we must know that repeatibility is of great importance to qualify and quantify. But when it comes to detect traces of this band (the presence of talc) an increase in resolution will help us.
This band allows us to calculate the signal to noise ratio of the instrument.
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We perform the analysis of the sample in a certain number of occasions, and then we make the standard deviation of the absorbance values obtained to calculate the precission.
The intensity of this band also increase or decrease according to the resolution of the equipment. But we must know that the repeatability will also be better or worse depending on the resolution and therefore the intensity of the band.
So here is a dilemma: Do we want a greater intensity of the band? or Do we want a better repeatability?.
It is clear that both options have their advantages, but we must know that repeatibility is of great importance to qualify and quantify. But when it comes to detect traces of this band (the presence of talc) an increase in resolution will help us.
This band allows us to calculate the signal to noise ratio of the instrument.
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